Gene
adgrl1a
- ID
- ZDB-GENE-131127-267
- Name
- adhesion G protein-coupled receptor L1a
- Symbol
- adgrl1a Nomenclature History
- Previous Names
-
- lphn1a
- si:ch211-129o13.1 (1)
- zmp:0000001269
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to enable G protein-coupled receptor activity and latrotoxin receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to act upstream of or within cell surface receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in axon and presynaptic membrane. Is expressed in brain; eye; liver; and muscle. Orthologous to human ADGRL1 (adhesion G protein-coupled receptor L1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Harty et al., 2015
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Developmental delay, behavioral abnormalities, and neuropsychiatric disorders | 620065 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR000203 | GPS motif |
| Conserved_site | IPR017983 | GPCR, family 2, secretin-like, conserved site |
| Domain | IPR000922 | D-galactoside/L-rhamnose binding SUEL lectin domain |
| Domain | IPR001879 | GPCR, family 2, extracellular hormone receptor domain |
| Domain | IPR003112 | Olfactomedin-like domain |
| Domain | IPR003334 | GPCR, family 2, latrophilin, C-terminal |
| Domain | IPR017981 | GPCR, family 2-like, 7TM |
| Domain | IPR031234 | Latrophilin-1, , transmembrane domain |
| Family | IPR000832 | GPCR, family 2, secretin-like |
| Family | IPR003924 | GPCR, family 2, latrophilin |
| Homologous_superfamily | IPR036445 | GPCR family 2, extracellular hormone receptor domain superfamily |
| Homologous_superfamily | IPR043159 | D-galactoside/L-rhamnose binding SUEL lectin domain superfamily |
| Homologous_superfamily | IPR046338 | GAIN domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | D-galactoside/L-rhamnose binding SUEL lectin domain | D-galactoside/L-rhamnose binding SUEL lectin domain superfamily | GAIN domain superfamily | GPCR, family 2, extracellular hormone receptor domain | GPCR family 2, extracellular hormone receptor domain superfamily | GPCR, family 2, latrophilin | GPCR, family 2, latrophilin, C-terminal | GPCR, family 2-like, 7TM | GPCR, family 2, secretin-like | GPCR, family 2, secretin-like, conserved site | GPS motif | Latrophilin-1, , transmembrane domain | Olfactomedin-like domain |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9PJK3 | InterPro | 722 | |||||||||||||
| UniProtKB:F1Q9V2 | InterPro | 1519 | |||||||||||||
| UniProtKB:A0A8M9PZN0 | InterPro | 1524 | |||||||||||||
| UniProtKB:A0A8M9PQJ9 | InterPro | 705 | |||||||||||||
| UniProtKB:A0A8M9QAJ8 | InterPro | 1348 | |||||||||||||
| UniProtKB:A0AB32TJF3 | InterPro | 1502 | |||||||||||||
| UniProtKB:A0AB32TL47 | InterPro | 744 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
adgrl1a-201
(1)
|
Ensembl | 5,559 nt | ||
| mRNA |
adgrl1a-202
(1)
|
Ensembl | 5,574 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance