Gene

ptprbl

ID
ZDB-GENE-130522-4
Name
protein tyrosine phosphatase receptor type B, like
Symbol
ptprbl Nomenclature History
Previous Names
  • zmp:0000000554 (1)
Type
protein_coding_gene
Location
Unmapped
Description
Acts upstream of or within blood vessel lumenization and establishment or maintenance of apical/basal cell polarity. Is expressed in intersegmental vessel. Human ortholog(s) of this gene implicated in angiosarcoma; breast angiosarcoma; carcinoma (multiple); central nervous system cancer (multiple); and sarcoma. Orthologous to human PTPRB (protein tyrosine phosphatase receptor type B).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Hayashi et al., 2013
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Hayashi et al., 2013
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ptprbl Human Ortholog
No data available
Associated With ptprbl Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003961 Fibronectin type III
Domain IPR041201 PTPRJ, transmembrane domain
Family IPR050713 Receptor-type Tyrosine-protein Phosphatases/Ushers
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR036116 Fibronectin type III superfamily
Domain Details Per Protein
Protein Additional Resources Length Fibronectin type III Fibronectin type III superfamily Immunoglobulin-like fold PTPRJ, transmembrane domain Receptor-type Tyrosine-protein Phosphatases/Ushers
UniProtKB:A0AB32TLT1 InterPro 924
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations