Gene
epx
- ID
- ZDB-GENE-130425-2
- Name
- eosinophil peroxidase
- Symbol
- epx Nomenclature History
- Previous Names
-
- zmp:0000000542
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease 1; cystic fibrosis; kidney failure (multiple); liver disease (multiple); and lung disease (multiple). Orthologous to human LPO (lactoperoxidase) and MPO (myeloperoxidase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Naef et al., 2025
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018097 | EGF-like calcium-binding, conserved site |
| Domain | IPR000436 | Sushi/SCR/CCP domain |
| Domain | IPR049883 | NOTCH1 EGF-like calcium-binding domain |
| Family | IPR019791 | Haem peroxidase, animal-type |
| Homologous_superfamily | IPR010255 | Haem peroxidase superfamily |
| Homologous_superfamily | IPR035976 | Sushi/SCR/CCP superfamily |
| Homologous_superfamily | IPR037120 | Haem peroxidase domain superfamily, animal type |
Domain Details Per Protein
| Protein | Additional Resources | Length | EGF-like calcium-binding, conserved site | Haem peroxidase, animal-type | Haem peroxidase domain superfamily, animal type | Haem peroxidase superfamily | NOTCH1 EGF-like calcium-binding domain | Sushi/SCR/CCP domain | Sushi/SCR/CCP superfamily |
|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0AB32TDT6 | InterPro | 816 |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance