Gene

il21

ID
ZDB-GENE-120510-4
Name
interleukin 21
Symbol
il21 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Predicted to have cytokine receptor binding activity. Predicted to be involved in immune response. Predicted to localize to extracellular region. Human ortholog(s) of this gene implicated in asthma and common variable immunodeficiency. Is expressed in several structures, including gill; heart; immune system; liver; and muscle. Orthologous to human IL21 (interleukin 21).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
5 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With il21 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
common variable immunodeficiency 11 Alliance ?Immunodeficiency, common variable, 11 615767
Associated With il21 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR003443 Interleukin-15/Interleukin-21 family
Homologous_superfamily IPR009079 Four-helical cytokine-like, core
Domain Details Per Protein
Protein Length Four-helical cytokine-like, core Interleukin-15/Interleukin-21 family
UniProtKB:A1YYP5 151
UniProtKB:A0A8M2BKC7 144
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations