ZFIN is now using GRCz12tu for Genomic Data
Gene
fbxo11b
- ID
- ZDB-GENE-110810-2
- Name
- F-box protein 11b
- Symbol
- fbxo11b Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable zinc ion binding activity. Human ortholog(s) of this gene implicated in breast carcinoma and lung non-small cell carcinoma. Orthologous to human FBXO11 (F-box protein 11).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| intellectual developmental disorder with dysmorphic facies and behavioral abnormalities | Alliance | Intellectual developmental disorder with dysmorphic facies and behavioral abnormalities | 618089 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001810 | F-box domain |
| Domain | IPR003126 | Zinc finger, UBR-type |
| Domain | IPR006633 | Carbohydrate-binding/sugar hydrolysis domain |
| Domain | IPR039448 | Right handed beta helix domain |
| Domain | IPR047504 | F-box only protein 11, UBR-box |
| Domain | IPR047505 | F-box only protein 11, F-box domain |
| Family | IPR051550 | SCF Complex Subunits and Alginate Epimerases |
| Homologous_superfamily | IPR011050 | Pectin lyase fold/virulence factor |
| Homologous_superfamily | IPR012334 | Pectin lyase fold |
| Homologous_superfamily | IPR036047 | F-box-like domain superfamily |
| Repeat | IPR006626 | Parallel beta-helix repeat |
| Repeat | IPR022441 | Parallel beta-helix repeat-2 |
Domain Details Per Protein
| Protein | Additional Resources | Length | Carbohydrate-binding/sugar hydrolysis domain | F-box domain | F-box-like domain superfamily | F-box only protein 11, F-box domain | F-box only protein 11, UBR-box | Parallel beta-helix repeat | Parallel beta-helix repeat-2 | Pectin lyase fold | Pectin lyase fold/virulence factor | Right handed beta helix domain | SCF Complex Subunits and Alginate Epimerases | Zinc finger, UBR-type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:U3JA39 | InterPro | 879 | ||||||||||||
| UniProtKB:A0A8M9QEP9 | InterPro | 843 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
fbxo11a-203
(1)
|
Ensembl | 4,423 nt | ||
| ncRNA |
ottdart00000058448
(1)
|
Ensembl | 736 nt | ||
| ncRNA |
ottdart00000058449
(1)
|
Ensembl | 385 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers
- Comparative Orthology
- Alliance