Gene
myh11b
- ID
- ZDB-GENE-101124-2
- Name
- myosin, heavy chain 11b, smooth muscle
- Symbol
- myh11b Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to have ATP binding activity; actin filament binding activity; and motor activity. Predicted to be involved in regulation of microtubule motor activity. Predicted to localize to myosin complex. Human ortholog(s) of this gene implicated in patent ductus arteriosus and thoracic aortic aneurysm. Orthologous to human MYH11 (myosin heavy chain 11).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| thoracic aortic aneurysm | Alliance | Aortic aneurysm, familial thoracic 4 | 132900 |
| Megacystis-microcolon-intestinal hypoperistalsis syndrome 2 | 619351 | ||
| Visceral myopathy 2 | 619350 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Binding_site | IPR000048 | IQ motif, EF-hand binding site |
| Domain | IPR001609 | Myosin head, motor domain |
| Domain | IPR002928 | Myosin tail |
| Domain | IPR004009 | Myosin, N-terminal, SH3-like |
| Homologous_superfamily | IPR008989 | Myosin S1 fragment, N-terminal |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR036961 | Kinesin motor domain superfamily |
Domain Details Per Protein
| Protein | Length | IQ motif, EF-hand binding site | Kinesin motor domain superfamily | Myosin head, motor domain | Myosin, N-terminal, SH3-like | Myosin S1 fragment, N-terminal | Myosin tail | P-loop containing nucleoside triphosphate hydrolase |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M6Z539
|
2005 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| mRNA |
myh11b-201
(1)
|
Havana | 6302 nt |
Interactions and Pathways
No data available
Plasmids
No data available