ZFIN is now using GRCz12tu for Genomic Data
Gene
aff4
- ID
- ZDB-GENE-100910-5
- Name
- AF4/FMR2 family, member 4
- Symbol
- aff4 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable transcription coregulator activity. Predicted to be involved in DNA-templated transcription elongation; nervous system process; and regulation of DNA-templated transcription. Predicted to be located in nucleus. Predicted to be part of super elongation complex. Is expressed in telencephalon. Orthologous to human AFF4 (ALF transcription elongation factor 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Diotel et al., 2015
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| CHOPS syndrome | 616368 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | AF4/FMR2, C-terminal homology domain | AF4/FMR2 family |
|---|---|---|---|---|
| UniProtKB:A0A8N7TEI3 | InterPro | 1078 | ||
| UniProtKB:A0A8M2BL85 | InterPro | 1085 | ||
| UniProtKB:I3ISK1 | InterPro | 1083 | ||
| UniProtKB:A0AB32TBH8 | InterPro | 1076 | ||
| UniProtKB:A0AB32TE70 | InterPro | 1025 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers