Gene
ralgapa1
- ID
- ZDB-GENE-080806-1
- Name
- Ral GTPase activating protein catalytic subunit alpha 1
- Symbol
- ralgapa1 Nomenclature History
- Previous Names
-
- garnl1
- tulip1 (1)
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to have GTPase activator activity. Involved in brain development. Predicted to localize to cytoplasm. Is expressed in head. Orthologous to human RALGAPA1 (Ral GTPase activating protein catalytic subunit alpha 1).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 1 figure from Shimojima et al., 2009
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Shimojima et al., 2009
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
Neurodevelopmental disorder with hypotonia, neonatal respiratory insufficiency, and thermodysregulation | 618797 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR000331 | Rap/Ran-GAP domain |
Domain | IPR046859 | Ral GTPase-activating protein subunit alpha/beta, N-terminal domain |
Family | IPR027107 | Tuberin/Ral GTPase-activating protein subunit alpha |
Homologous_superfamily | IPR016024 | Armadillo-type fold |
Homologous_superfamily | IPR035974 | Rap/Ran-GAP superfamily |
Domain Details Per Protein
Protein | Length | Armadillo-type fold | Ral GTPase-activating protein subunit alpha/beta, N-terminal domain | Rap/Ran-GAP domain | Rap/Ran-GAP superfamily | Tuberin/Ral GTPase-activating protein subunit alpha |
---|---|---|---|---|---|---|
UniProtKB:A0A8M9P0D3
|
2471 | |||||
UniProtKB:A0A8M9PL41
|
2499 | |||||
UniProtKB:A0A8M9PL46
|
2105 | |||||
UniProtKB:A0A8M9PEK0
|
2518 | |||||
UniProtKB:A0A8M9PP64
|
2124 | |||||
UniProtKB:A0A8M9P0D7
|
2066 | |||||
UniProtKB:A0A8M9PEK4
|
2171 | |||||
UniProtKB:A0A8M9PP58
|
2515 | |||||
UniProtKB:A0A8M9P993
|
2460 | |||||
UniProtKB:A0A8M9P998
|
2152 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
mRNA |
ralgapa1-201
(1)
|
Ensembl | 6846 nt | |
mRNA |
ralgapa1-202
(1)
|
Ensembl | 6344 nt | |
mRNA |
ralgapa1-203
(1)
|
Havana | 7844 nt | |
mRNA |
ralgapa1-204
(1)
|
Havana | 593 nt | |
mRNA |
ralgapa1-206
(1)
|
Havana | 926 nt | |
mRNA |
ralgapa1-207
(1)
|
Ensembl | 6459 nt | |
mRNA |
ralgapa1-208
(1)
|
Ensembl | 6366 nt | |
ncRNA |
ralgapa1-004
(1)
|
Havana | 422 nt |
Interactions and Pathways
No data available
Plasmids
No data available