Gene

sergef

ID
ZDB-GENE-061220-11
Name
secretion regulating guanine nucleotide exchange factor
Symbol
sergef Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 25 Mapping Details/Browsers
Description
Predicted to be involved in negative regulation of protein secretion. Predicted to be active in cytoplasm and nucleus. Orthologous to human SERGEF (secretion regulating guanine nucleotide exchange factor).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa6797Allele with one point mutationUnknownPremature StopENU
sa38010Allele with one point mutationUnknownPremature StopENU
Zebrafish International Resource Center (ZIRC) (order this)
European Zebrafish Resource Center (EZRC) (order this)
1 - 2 of 2
Show
Sequence Targeting Reagents
No data available
Human Disease
Associated With sergef Human Ortholog
No data available
Associated With sergef Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR051210 Ubiquitin ligases and GEF domain-containing protein
Homologous_superfamily IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II
Repeat IPR000408 Regulator of chromosome condensation, RCC1
1 - 3 of 3
Domain Details Per Protein
Protein Additional Resources Length Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II Regulator of chromosome condensation, RCC1 Ubiquitin ligases and GEF domain-containing protein
UniProtKB:A0A8M9PED2 InterPro 397
UniProtKB:F1QKS2 InterPro 397
1 - 2 of 2
Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 25
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA sergef-201 (1)
Ensembl
Ensembl 1,886 nt
ZFIN BLAST
ncRNA sergef-002 (1)
Ensembl
Ensembl 742 nt
ZFIN BLAST
1 - 2 of 2
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH73-334L12ZFIN Curated Data
Contained inBACCH211-146D6
1 - 2 of 2
Show
Sequences
Type Accession # Sequence Length (nt/aa) Analysis
RNARefSeq:XM_068219113 (1)1855 nt
ZFIN BLASTNCBI BLASTEnsemblUCSC BLAT
GenomicGenBank:BX001042 (1)168195 nt
MegaBLASTEnsembl
PolypeptideUniProtKB:A0A8M9PED2 (1)397 aa
ZFIN BLASTSIB BLASTEnsembl Protein Blast
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanSERGEF11
Amino acid sequence comparison (1)
Conserved genome location (synteny) (2)
Citations
TSV
1 - 2 of 2
Show
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.