Gene
rorb
- ID
- ZDB-GENE-061204-2
- Name
- RAR-related orphan receptor B
- Symbol
- rorb Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in alar plate midbrain region; immature eye; and nervous system. Orthologous to human RORB (RAR related orphan receptor B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 30 figures from 10 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu943 (14 images)
- dq017626 (21 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| {Epilepsy, idiopathic generalized, susceptibility to, 15} | 618357 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000536 | Nuclear hormone receptor, ligand-binding domain |
| Domain | IPR001628 | Zinc finger, nuclear hormone receptor-type |
| Domain | IPR044101 | Retinoid-related orphan receptors, DNA-binding domain |
| Family | IPR001723 | Nuclear hormone receptor |
| Family | IPR003079 | Nuclear receptor ROR |
| Homologous_superfamily | IPR013088 | Zinc finger, NHR/GATA-type |
| Homologous_superfamily | IPR035500 | Nuclear hormone receptor-like domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Nuclear hormone receptor | Nuclear hormone receptor, ligand-binding domain | Nuclear hormone receptor-like domain superfamily | Nuclear receptor ROR | Retinoid-related orphan receptors, DNA-binding domain | Zinc finger, NHR/GATA-type | Zinc finger, nuclear hormone receptor-type |
|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A3R3J9 | InterPro | 466 |
Interactions and Pathways
No data available
Plasmids
No data available