Gene

aldoca

ID
ZDB-GENE-050706-128
Name
aldolase C, fructose-bisphosphate, a
Symbol
aldoca Nomenclature History
Previous Names
  • aldocl (1)
  • wu:fj56h04
  • zebrin II (1)
  • zgc:112357
Type
protein_coding_gene
Location
Chr: 15 Mapping Details/Browsers
Description
Predicted to enable fructose-bisphosphate aldolase activity. Predicted to be involved in fructose 1,6-bisphosphate metabolic process and glycolytic process. Predicted to be active in cytosol. Is expressed in brain. Human ortholog(s) of this gene implicated in autoimmune disease of the nervous system. Orthologous to human ALDOC (aldolase, fructose-bisphosphate C).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
10 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With aldoca Human Ortholog
No data available
Associated With aldoca Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Conserved_site IPR029768 Fructose-bisphosphate aldolase class-I active site
Domain IPR000719 Protein kinase domain
Domain IPR045270 Serine/Threonine Kinase AGC, catalytic domain
Family IPR000741 Fructose-bisphosphate aldolase, class-I
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Homologous_superfamily IPR013785 Aldolase-type TIM barrel
Domain Details Per Protein
Protein Additional Resources Length Aldolase-type TIM barrel Fructose-bisphosphate aldolase, class-I Fructose-bisphosphate aldolase class-I active site Protein kinase domain Protein kinase-like domain superfamily Serine/Threonine Kinase AGC, catalytic domain Serine/threonine-protein kinase, active site
UniProtKB:Q4KMC8 InterPro 364
UniProtKB:F1QC70 InterPro 364
UniProtKB:A0AB32T8F5 InterPro 662
UniProtKB:A0AB32TA60 InterPro 692
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA aldoca-201 (1)
Ensembl
Ensembl 2,174 nt
ZFIN BLAST
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-aldoc monoclonal Mouse
  • IHC
 21
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations
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