Gene
tmem127
- ID
- ZDB-GENE-050522-97
- Name
- transmembrane protein 127
- Symbol
- tmem127 Nomenclature History
- Previous Names
-
- zgc:109899
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to be involved in regulation of TOR signaling. Predicted to act upstream of or within negative regulation of TOR signaling and negative regulation of cell population proliferation. Predicted to be located in plasma membrane. Predicted to be active in membrane. Human ortholog(s) of this gene implicated in pheochromocytoma. Orthologous to human TMEM127 (transmembrane protein 127).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:109899 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| pheochromocytoma | Alliance | {Pheochromocytoma, susceptibility to} | 171300 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Transmembrane protein 127 | Transmembrane protein 127, transmembrane region |
|---|---|---|---|---|
| UniProtKB:Q504G0 | InterPro | 237 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
tmem127-201
(1)
|
Ensembl | 1,548 nt | ||
| mRNA |
tmem127-202
(1)
|
Ensembl | 573 nt |
Interactions and Pathways
No data available
Plasmids
No data available