Gene

katna1

ID

ZDB-GENE-050522-514

Name

katanin p60 (ATPase containing) subunit A 1

Symbol

katna1 Nomenclature History

Previous Names

si:dkey-15j16.1
zgc:110580 (1)

Type

protein_coding_gene

Location

Chr: 20 Mapping Details/Browsers

Description

Predicted to enable ATP hydrolysis activity and microtubule severing ATPase activity. Acts upstream of or within axon extension and cytoplasmic microtubule organization. Predicted to be located in midbody and mitotic spindle pole. Predicted to be active in cytoplasm and spindle. Orthologous to human KATNA1 (katanin catalytic subunit A1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:110580 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 5 figures from Butler et al., 2010
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With katna1 Human Ortholog

No data available

Associated With katna1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR003960	ATPase, AAA-type, conserved site
Domain	IPR003593	AAA+ ATPase domain
Domain	IPR003959	ATPase, AAA-type, core
Domain	IPR015415	Spastin/Vps4, C-terminal
Domain	IPR041569	AAA ATPase, AAA+ lid domain
Domain	IPR048611	Katanin p60 ATPase-containing subunit A1, MIT domain
Domain	IPR048612	Katanin p60 ATPase-containing subunit A1, AAA domain
Family	IPR028596	Katanin p60 subunit A1
Family	IPR050304	Microtubule-severing AAA ATPase
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase