Gene

gng2

ID

ZDB-GENE-050417-59

Name

guanine nucleotide binding protein (G protein), gamma 2

Symbol

gng2 Nomenclature History

Previous Names

zgc:110302

Type

protein_coding_gene

Location

Chr: 13 Mapping Details/Browsers

Description

Predicted to have G-protein beta-subunit binding activity. Involved in sprouting angiogenesis and vascular endothelial growth factor receptor signaling pathway. Localizes to cytosol and membrane. Is expressed in cardiovascular system and nervous system. Orthologous to human GNG2 (G protein subunit gamma 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

13 figures from 4 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

MGC:110302 (15 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With gng2 Human Ortholog

No data available

Associated With gng2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000477	Reverse transcriptase domain
Domain	IPR001584	Integrase, catalytic core
Domain	IPR015898	G-protein gamma-like domain
Domain	IPR040676	Domain of unknown function DUF5641
Domain	IPR041588	Integrase zinc-binding domain
Family	IPR001770	G-protein, gamma subunit
Family	IPR008042	Retrotransposon, Pao
Homologous_superfamily	IPR012337	Ribonuclease H-like superfamily
Homologous_superfamily	IPR036284	G-protein gamma-like domain superfamily
Homologous_superfamily	IPR036397	Ribonuclease H superfamily
Homologous_superfamily	IPR043128	Reverse transcriptase/Diguanylate cyclase domain
Homologous_superfamily	IPR043502	DNA/RNA polymerase superfamily

Domain Details Per Protein

Protein	Length	DNA/RNA polymerase superfamily	Domain of unknown function DUF5641	G-protein gamma-like domain	G-protein gamma-like domain superfamily	G-protein, gamma subunit	Integrase, catalytic core	Integrase zinc-binding domain	Retrotransposon, Pao	Reverse transcriptase/Diguanylate cyclase domain	Reverse transcriptase domain	Ribonuclease H-like superfamily	Ribonuclease H superfamily
UniProtKB:A0A8M9QJN0 InterPro	1954
UniProtKB:Q15KE4 InterPro	71

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	gng2-201 (1) Ensembl	Havana	1213 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	gng2-202 (1) Ensembl	Havana	500 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	gng2-203 (1) Ensembl	Havana	872 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	gng2-204 (1) Ensembl	Havana	979 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	gng2-205 (1) Ensembl	Havana	785 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	gng2-206 (1) Ensembl	Havana	540 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations