rgs5b

ID

ZDB-GENE-050417-359

Name

regulator of G protein signaling 5b

Symbol

rgs5b Nomenclature History

Previous Names

zgc:110206

Type

protein_coding_gene

Location

Chr: 2 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable GTPase activator activity. Predicted to be involved in negative regulation of G protein-coupled receptor signaling pathway. Predicted to be active in cytoplasmic side of plasma membrane. Human ortholog(s) of this gene implicated in colorectal adenocarcinoma and essential hypertension. Orthologous to several human genes including RGS16 (regulator of G protein signaling 16).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:110206 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With rgs5b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
essential hypertension	Alliance	[Blood pressure regulation QTL]	145500

Associated With rgs5b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR016137	RGS domain
Homologous_superfamily	IPR024066	RGS, subdomain 1/3
Homologous_superfamily	IPR036305	RGS domain superfamily
Homologous_superfamily	IPR044926	RGS, subdomain 2