Gene
hspa14
- ID
- ZDB-GENE-041210-73
- Name
- heat shock protein 14
- Symbol
- hspa14 Nomenclature History
- Previous Names
-
- fb24c02
- si:dkey-153k10.2
- wu:fb24c02
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to enable ATP hydrolysis activity; heat shock protein binding activity; and protein folding chaperone. Predicted to be involved in chaperone cofactor-dependent protein refolding and protein refolding. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Predicted to colocalize with ribosome. Orthologous to human HSPA14 (heat shock protein family A (Hsp70) member 14).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR042049 | Heat shock 70kDa protein 14, nucleotide-binding domain |
| Family | IPR013126 | Heat shock protein 70 family |
| Homologous_superfamily | IPR029047 | Heat shock protein 70kD, peptide-binding domain superfamily |
| Homologous_superfamily | IPR043129 | ATPase, nucleotide binding domain |
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Domain Details Per Protein
| Protein | Additional Resources | Length | ATPase, nucleotide binding domain | Heat shock 70kDa protein 14, nucleotide-binding domain | Heat shock protein 70 family | Heat shock protein 70kD, peptide-binding domain superfamily |
|---|---|---|---|---|---|---|
| UniProtKB:Q5RGE6 | InterPro | 504 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| aberrant processed transcript |
hspa14-202
(1)
|
Ensembl | 571 nt | ||
| mRNA |
hspa14-201
(1)
|
Ensembl | 2,249 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-153K10 | ZFIN Curated Data | |
| Contains | SNP | rs3727754 | ZFIN Curated Data | |
| Contains | SNP | rs3727755 | ZFIN Curated Data | |
| Contains | SNP | rs3727756 | ZFIN Curated Data | |
| Encodes | EST | fb24c02 | ||
| Encodes | cDNA | MGC:158639 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001045076 (1) | 2242 nt | ||
| Genomic | GenBank:BX901962 (1) | 182550 nt | ||
| Polypeptide | UniProtKB:Q5RGE6 (1) | 504 aa |
- Pei, W., Xu, L., Huang, S.C., Pettie, K., Idol, J., Rissone, A., Jimenez, E., Sinclair, J.W., Slevin, C., Varshney, G.K., Jones, M., Carrington, B., Bishop, K., Huang, H., Sood, R., Lin, S., Burgess, S.M. (2018) Guided genetic screen to identify genes essential in the regeneration of hair cells and other tissues. NPJ Regenerative medicine. 3:11
- Xu, K., Xu, H., Han, Z. (2018) Genome-Wide Identification of Hsp70 Genes in the Large Yellow Croaker (Larimichthys crocea) and Their Regulated Expression Under Cold and Heat Stress. Genes. 9(12)
- Liu, C., Xu, H., Lam, S.H., and Gong, Z. (2013) Selection of Reliable Biomarkers from PCR Array Analyses Using Relative Distance Computational Model: Methodology and Proof-of-Concept Study. PLoS One. 8(12):e83954
- Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
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