Gene
dnai1.1
- ID
- ZDB-GENE-040910-7
- Name
- dynein, axonemal, intermediate chain 1, paralog 1
- Symbol
- dnai1.1 Nomenclature History
- Previous Names
-
- dnai1
- si:ch73-182i17.2
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Acts upstream of or within determination of heart left/right asymmetry. Predicted to be located in cell projection; cytoplasm; and microtubule. Predicted to be part of dynein complex. Human ortholog(s) of this gene implicated in Kartagener syndrome and primary ciliary dyskinesia 1. Orthologous to human DNAI1 (dynein axonemal intermediate chain 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Zhao et al., 2013
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| primary ciliary dyskinesia 1 | Alliance | Ciliary dyskinesia, primary, 1, with or without situs inversus | 244400 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Dynein Intermediate Chain | WD40 repeat | WD40-repeat-containing domain superfamily | WD40/YVTN repeat-like-containing domain superfamily |
|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9PUJ5 | InterPro | 105 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
dnai1.1-201
(1)
|
Ensembl | 1,662 nt | ||
| mRNA |
dnai1.1-202
(1)
|
Ensembl | 560 nt | ||
| mRNA |
dnai1.1-204
(1)
|
Ensembl | 792 nt | ||
| mRNA |
dnai1.1-205
(1)
|
Ensembl | 1,960 nt | ||
| ncRNA |
dnai1.1-004
(1)
|
Ensembl | 633 nt |
Interactions and Pathways
No data available
Plasmids
No data available