Gene
ighv14-1
- ID
- ZDB-GENE-040514-42
- Name
- immunoglobulin heavy variable 14-1
- Symbol
- ighv14-1 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to enable antigen binding activity. Predicted to be involved in immunoglobulin mediated immune response. Orthologous to several human genes including IGHV3-16 (immunoglobulin heavy variable 3-16 (non-functional)); IGHV3-35 (immunoglobulin heavy variable 3-35 (non-functional)); and IGHV3OR16-17 (immunoglobulin heavy variable 3/OR16-17 (non-functional)).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
No data available
Human Disease
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
No data available
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ighv14-1-201
(1)
|
Ensembl | 374 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-204F11 |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | GenBank:AY646270 (1) | 583 nt | ||
| Genomic | GenBank:BX649502 | 247387 nt | ||
| Polypeptide | GenPept:AAU06731 (1) | 194 aa |
No data available
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Jiang, N., Weinstein, J.A., Penland, L., White, R.A., Fisher, D.S., and Quake, S.R. (2011) Determinism and stochasticity during maturation of the zebrafish antibody repertoire. Proceedings of the National Academy of Sciences of the United States of America. 108(13):5348-53
- Weinstein, J.A., Jiang, N., White, R.A. 3rd, Fisher, D.S., and Quake, S.R. (2009) High-throughput sequencing of the zebrafish antibody repertoire. Science (New York, N.Y.). 324(5928):807-810
- Danilova, N., Bussmann, J., Jekosch, K., and Steiner, L.A. (2005) The immunoglobulin heavy-chain locus in zebrafish: identification and expression of a previously unknown isotype, immunoglobulin Z. Nature immunology. 6(3):295-302
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