Gene

pccb

ID
ZDB-GENE-040426-2467
Name
propionyl-CoA carboxylase subunit beta
Symbol
pccb Nomenclature History
Previous Names
  • zgc:85813
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to enable propionyl-CoA carboxylase activity. Predicted to be located in mitochondrial matrix. Predicted to be active in mitochondrion. Is expressed in several structures, including alar plate midbrain region; musculature system; optic tectum; optic vesicle; and pronephros. Human ortholog(s) of this gene implicated in amino acid metabolic disorder and propionic acidemia. Orthologous to human PCCB (propionyl-CoA carboxylase subunit beta).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
8 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pccb Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
propionic acidemia Alliance Propionicacidemia 606054
1 - 1 of 1
Associated With pccb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR011762 Acetyl-coenzyme A carboxyltransferase, N-terminal
Domain IPR011763 Acetyl-coenzyme A carboxyltransferase, C-terminal
Domain IPR034733 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta
Family IPR051047 Acyl-CoA Carboxylase Beta Subunit
Homologous_superfamily IPR029045 ClpP/crotonase-like domain superfamily
1 - 5 of 5
Domain Details Per Protein
Protein Additional Resources Length Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta Acetyl-coenzyme A carboxyltransferase, C-terminal Acetyl-coenzyme A carboxyltransferase, N-terminal Acyl-CoA Carboxylase Beta Subunit ClpP/crotonase-like domain superfamily
UniProtKB:Q6NWC8 InterPro 557
UniProtKB:B0V0X1 InterPro 555
1 - 2 of 2
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA pccb-201 (1)
Ensembl
Ensembl 2,228 nt
ZFIN BLAST
1 - 1 of 1
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations
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