Gene
parp2
- ID
- ZDB-GENE-031113-6
- Name
- poly (ADP-ribose) polymerase 2
- Symbol
- parp2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to enable NAD+ poly-ADP-ribosyltransferase activity. Predicted to be involved in double-strand break repair. Predicted to act upstream of or within DNA damage response. Predicted to be located in chromosome and nucleoplasm. Predicted to be active in nucleolus. Is expressed in brain; head; and proliferative region. Orthologous to human PARP2 (poly(ADP-ribose) polymerase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2001
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb996 (6 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR004102 | Poly(ADP-ribose) polymerase, regulatory domain |
| Domain | IPR004170 | WWE domain |
| Domain | IPR008893 | WGR domain |
| Domain | IPR012317 | Poly(ADP-ribose) polymerase, catalytic domain |
| Domain | IPR018123 | WWE domain, subgroup |
| Family | IPR050800 | ADP-ribosyltransferase diphtheria toxin-like |
| Homologous_superfamily | IPR036616 | Poly(ADP-ribose) polymerase, regulatory domain superfamily |
| Homologous_superfamily | IPR036930 | WGR domain superfamily |
| Homologous_superfamily | IPR037197 | WWE domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | ADP-ribosyltransferase diphtheria toxin-like | Poly(ADP-ribose) polymerase, catalytic domain | Poly(ADP-ribose) polymerase, regulatory domain | Poly(ADP-ribose) polymerase, regulatory domain superfamily | WGR domain | WGR domain superfamily | WWE domain | WWE domain, subgroup | WWE domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:F1QAF7 | InterPro | 648 | |||||||||
| UniProtKB:A0A8M9QIR2 | InterPro | 649 |
Interactions and Pathways
No data available
Plasmids
No data available