Gene
cul2
- ID
- ZDB-GENE-030131-8032
- Name
- cullin 2
- Symbol
- cul2 Nomenclature History
- Previous Names
-
- fj48a06
- sb:eu1026
- wu:fj48a06
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Predicted to enable protein-macromolecule adaptor activity and ubiquitin protein ligase binding activity. Acts upstream of or within chordate embryonic development and vasculature development. Predicted to be located in nuclear lumen. Predicted to be part of Cul2-RING ubiquitin ligase complex and SCF ubiquitin ligase complex. Orthologous to human CUL2 (cullin 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu1026 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Maeda et al., 2008
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR016157 | Cullin, conserved site |
| Domain | IPR001373 | Cullin, N-terminal |
| Domain | IPR016158 | Cullin homology domain |
| Domain | IPR019559 | Cullin protein, neddylation domain |
| Family | IPR045093 | Cullin |
| Homologous_superfamily | IPR016159 | Cullin repeat-like-containing domain superfamily |
| Homologous_superfamily | IPR036317 | Cullin homology domain superfamily |
| Homologous_superfamily | IPR036388 | Winged helix-like DNA-binding domain superfamily |
| Homologous_superfamily | IPR036390 | Winged helix DNA-binding domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Cullin | Cullin, conserved site | Cullin homology domain | Cullin homology domain superfamily | Cullin, N-terminal | Cullin protein, neddylation domain | Cullin repeat-like-containing domain superfamily | Winged helix DNA-binding domain superfamily | Winged helix-like DNA-binding domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9P612 | InterPro | 745 |
Interactions and Pathways
No data available
Plasmids
No data available