Gene
senp1
- ID
- ZDB-GENE-030131-6462
- Name
- SUMO specific peptidase 1
- Symbol
- senp1 Nomenclature History
- Previous Names
-
- fj98g07
- si:dkey-21c19.3
- wu:fj98g07 (1)
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to enable deSUMOylase activity. Predicted to be involved in protein desumoylation. Predicted to act upstream of or within proteolysis. Predicted to be active in nucleus. Orthologous to human SENP1 (SUMO specific peptidase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| la028524Tg | Transgenic insertion | Unknown | Unknown | DNA | |
| sa14994 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa18189 | Allele with one point mutation | Unknown | Premature Stop | ENU |
1 - 3 of 3
Show
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Papain-like cysteine peptidase superfamily | Ulp1 protease family, C-terminal catalytic domain |
|---|---|---|---|---|
| UniProtKB:A0A8M9PWZ7 | InterPro | 729 | ||
| UniProtKB:E7F9B8 | InterPro | 729 |
1 - 2 of 2
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
si:dkey-21c19.3-201
(1)
|
Ensembl | 3,036 nt | ||
| ncRNA |
si:dkey-21c19.3-002
(1)
|
Ensembl | 840 nt |
1 - 2 of 2
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-21C19 | ZFIN Curated Data | |
| Encodes | EST | fj98g07 |
1 - 2 of 2
Show
| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_001343481 (1) | 3686 nt | ||
| Genomic | GenBank:BX005414 (1) | 236036 nt | ||
| Polypeptide | UniProtKB:A0A8M9PWZ7 (1) | 729 aa |
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Varshney, G.K., Lu, J., Gildea, D., Huang, H., Pei, W., Yang, Z., Huang, S.C., Schoenfeld, D.S., Pho, N., Casero, D., Hirase, T., Mosbrook-Davis, D.M., Zhang, S., Jao, L.E., Zhang, B., Woods, I.G., Zimmerman, S., Schier, A.F., Wolfsberg, T., Pellegrini, M., Burgess, S.M., and Lin, S. (2013) A large-scale zebrafish gene knockout resource for the genome-wide study of gene function. Genome research. 23(4):727-735
- Wang, D., Jao, L.E., Zheng, N., Dolan, K., Ivey, J., Zonies, S., Wu, X., Wu, K., Yang, H., Meng, Q., Zhu, Z., Zhang, B., Lin, S., and Burgess, S.M. (2007) Efficient genome-wide mutagenesis of zebrafish genes by retroviral insertions. Proceedings of the National Academy of Sciences of the United States of America. 104(30):12428-12433
1 - 3 of 3
Show