Gene
med7
- ID
- ZDB-GENE-030131-4823
- Name
- mediator complex subunit 7
- Symbol
- med7 Nomenclature History
- Previous Names
-
- crsp9 (1)
- wu:fd99d12
- zgc:56241
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to enable transcription coregulator activity. Predicted to act upstream of or within regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of mediator complex. Orthologous to human MED7 (mediator complex subunit 7).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:56241 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
Targeting Reagent | Created Alleles | Citations |
---|---|---|
CRISPR1-med7 | (2) | |
CRISPR2-med7 | (2) | |
MO1-med7 | N/A | Montasser et al., 2018 |
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Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Additional Resources | Length | Immune Modulating & Transcription Coactivator | Mediator complex, subunit Med7 | Mediator complex, subunit Med7/Med21-like | Mediator complex, subunit Med7 superfmaily |
---|---|---|---|---|---|---|
UniProtKB:Q7ZV35 | InterPro | 241 |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
Relationship | Marker Type | Marker | Accession Numbers | Citations |
---|---|---|---|---|
Contained in | BAC | CH73-22O18 | ZFIN Curated Data | |
Contained in | BAC | DKEY-14M2 | ZFIN Curated Data | |
Encodes | EST | fd99d12 | ||
Encodes | cDNA | MGC:56241 | ZFIN Curated Data | |
Encodes | cDNA | MGC:174096 | ZFIN Curated Data |
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Type | Accession # | Sequence | Length (nt/aa) | Analysis |
---|---|---|---|---|
RNA | RefSeq:NM_199741 (1) | 1015 nt | ||
Genomic | GenBank:BX088721 (1) | 231054 nt | ||
Polypeptide | UniProtKB:Q7ZV35 (1) | 241 aa |
- Montasser, M.E., O'Hare, E.A., Wang, X., Howard, A.D., McFarland, R., Perry, J.A., Ryan, K.A., Rice, K., Jaquish, C.E., Shuldiner, A.R., Miller, M., Mitchell, B.D., Zaghloul, N.A., Chang, Y.C. (2018) An APOO Pseudogene on Chromosome 5q is Associated with LDL-C Levels. Circulation. 138(13):1343-1355
- Unal Eroglu, A., Mulligan, T.S., Zhang, L., White, D.T., Sengupta, S., Nie, C., Lu, N.Y., Qian, J., Xu, L., Pei, W., Burgess, S.M., Saxena, M.T., Mumm, J.S. (2018) Multiplexed CRISPR/Cas9 Targeting of Genes Implicated in Retinal Regeneration and Degeneration. Frontiers in cell and developmental biology. 6:88
- Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
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