lgals3b

ID

ZDB-GENE-030131-4324

Name

lectin, galactoside binding soluble 3b

Symbol

lgals3b Nomenclature History

Previous Names

Drgal3 (1)
lgals3l
fc90g02
wu:fc90g02
zgc:123117

Type

protein_coding_gene

Location

Chr: 17 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable IgE binding activity; disaccharide binding activity; and laminin binding activity. Predicted to be involved in several processes, including leukocyte chemotaxis; negative regulation of extrinsic apoptotic signaling pathway; and positive regulation of calcium ion import. Predicted to be located in extracellular region. Predicted to be part of spliceosomal complex. Predicted to be active in several cellular components, including extracellular matrix; extracellular space; and immunological synapse. Is expressed in several structures, including digestive system; eye; mesoderm; ovary; and spleen. Human ortholog(s) of this gene implicated in asthma. Orthologous to human LGALS3 (galectin 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

13 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With lgals3b Human Ortholog

No data available

Associated With lgals3b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001079	Galectin, carbohydrate recognition domain
Family	IPR044156	Galectin-like
Homologous_superfamily	IPR013320	Concanavalin A-like lectin/glucanase domain superfamily