Gene
azin1b
- ID
- ZDB-GENE-030121-1
- Name
- antizyme inhibitor 1b
- Symbol
- azin1b Nomenclature History
- Previous Names
-
- azin1
- oazin (1)
- wu:fj32d12
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to enable ornithine decarboxylase activator activity and ornithine decarboxylase activity. Predicted to be involved in negative regulation of protein catabolic process; positive regulation of polyamine transmembrane transport; and putrescine biosynthetic process from arginine, via ornithine. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in esophagus squamous cell carcinoma; hepatocellular carcinoma; and liver cirrhosis. Orthologous to human AZIN1 (antizyme inhibitor 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7150958 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR022657 | Orn/DAP/Arg decarboxylase 2, conserved site |
| Domain | IPR022643 | Orn/DAP/Arg decarboxylase 2, C-terminal |
| Domain | IPR022644 | Orn/DAP/Arg decarboxylase 2, N-terminal |
| Family | IPR000183 | Ornithine/DAP/Arg decarboxylase |
| Family | IPR002433 | Ornithine decarboxylase |
| Family | IPR031178 | Antizyme inhibitor 1 |
| Homologous_superfamily | IPR009006 | Alanine racemase/group IV decarboxylase, C-terminal |
| Homologous_superfamily | IPR029066 | PLP-binding barrel |
Domain Details Per Protein
| Protein | Additional Resources | Length | Alanine racemase/group IV decarboxylase, C-terminal | Antizyme inhibitor 1 | Orn/DAP/Arg decarboxylase 2, conserved site | Orn/DAP/Arg decarboxylase 2, C-terminal | Orn/DAP/Arg decarboxylase 2, N-terminal | Ornithine/DAP/Arg decarboxylase | Ornithine decarboxylase | PLP-binding barrel |
|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q801V3 | InterPro | 436 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
azin1b-201
(1)
|
Ensembl | 2,808 nt | ||
| mRNA |
azin1b-202
(1)
|
Ensembl | 727 nt | ||
| mRNA |
azin1b-203
(1)
|
Ensembl | 2,446 nt |
Interactions and Pathways
No data available
Plasmids
No data available