Gene
cct3
- ID
- ZDB-GENE-020419-5
- Name
- chaperonin containing TCP1, subunit 3 (gamma)
- Symbol
- cct3 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to enable unfolded protein binding activity. Acts upstream of or within embryonic eye morphogenesis and negative regulation of retinal cell programmed cell death. Predicted to be located in cytoplasm. Predicted to be part of chaperonin-containing T-complex. Orthologous to human CCT3 (chaperonin containing TCP1 subunit 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:64132 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Neurodevelopmental disorder with speech or visual impairment and brain hypomyelination | 621034 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR002194 | Chaperonin TCP-1, conserved site |
| Family | IPR002423 | Chaperonin Cpn60/GroEL/TCP-1 family |
| Family | IPR012719 | T-complex protein 1, gamma subunit |
| Family | IPR017998 | Chaperone tailless complex polypeptide 1 (TCP-1) |
| Family | IPR053374 | TCP-1 chaperonin-containing T-complex |
| Family | IPR054827 | Thermosome subunit alpha |
| Homologous_superfamily | IPR027409 | GroEL-like apical domain superfamily |
| Homologous_superfamily | IPR027410 | TCP-1-like chaperonin intermediate domain superfamily |
| Homologous_superfamily | IPR027413 | GroEL-like equatorial domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Chaperone tailless complex polypeptide 1 (TCP-1) | Chaperonin Cpn60/GroEL/TCP-1 family | Chaperonin TCP-1, conserved site | GroEL-like apical domain superfamily | GroEL-like equatorial domain superfamily | T-complex protein 1, gamma subunit | TCP-1 chaperonin-containing T-complex | TCP-1-like chaperonin intermediate domain superfamily | Thermosome subunit alpha |
|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q8JHI7 | InterPro | 543 |
- Genome Browsers
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-cct3 | monoclonal | IgG1 , k | Mouse |
|
Santa Cruz Biotechnology, Inc.
|
2 |
Plasmids
No data available