Gene

krt4

ID
ZDB-GENE-000607-83
Name
keratin 4
Symbol
krt4 Nomenclature History
Previous Names
  • krt8 (1)
  • cb59 (1)
  • cytokeratin (1)
  • etID20321.6 (1)
  • wu:fa91a11
  • wu:fd19e09 (1)
  • wu:fl23c09 (1)
  • zf-K8 (1)
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to localize to keratin filament. Human ortholog(s) of this gene implicated in several diseases, including epidermolytic hyperkeratosis; hereditary mucosal leukokeratosis; ichthyosis (multiple); pachyonychia congenita; and palmoplantar keratosis (multiple). Is expressed in EVL; ectoderm; endocrine system; epidermis; and pharynx. Orthologous to several human genes including KRT8 (keratin 8).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
45 figures from 25 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With krt4 Human Ortholog
No data available
Associated With krt4 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018039 Intermediate filament protein, conserved site
Domain IPR032444 Keratin type II head
Domain IPR039008 Intermediate filament, rod domain
Family IPR003054 Keratin, type II
Domain Details Per Protein
Protein Length Intermediate filament protein, conserved site Intermediate filament, rod domain Keratin, type II Keratin type II head
UniProtKB:F1QK60 497
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations