ZFIN ID: ZDB-EXP-190718-8
Experiment Conditions Description: chemical treatment by environment: PD173074, amputation: caudal fin
chemical treatment by environment: PD173074
Name: chemical treatment by environment
Synonyms:
Definition: Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000238]
Name: PD173074
Synonyms: 1-tert-butyl-3-[2-{[4-(diethylamino)butyl]amino}-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]urea, PD 173074, PD-173074
Definition: A member of the class of ureas that is 1-tert-butylurea in which one of the hydrogens attached to N(3) is substituted by a pyrido[2,3-d]pyrimidin-7-yl group, which is itself substituted at positions 2 and 6 by a 4-(diethylamino)butyl]amino group and a 3,5-dimethoxyphenyl group, respectively. It is a FGF/VEGF receptor tyrosine kinase inhibitor.
Ontology: ChEBI [CHEBI:63448]  ( EBI )
amputation: caudal fin
Name: amputation
Synonyms:
Definition: Resection condtion in which all or part of an extremity such as the fin or tail are removed.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000172]
Name: caudal fin
Synonyms: tail, tail fin
Definition: Fin that is the most posterior median fin. It is composed of a complex of three modified centra and modified neural and hemal arches and spines.
Ontology: Anatomy Ontology [ZFA:0001058]
Publication: Ouyang et al., 2017