Gene

mcc

ID
ZDB-GENE-141210-1
Name
MCC regulator of WNT signaling pathway
Symbol
mcc Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Unmapped
Description
Predicted to have calcium ion binding activity. Involved in convergent extension involved in gastrulation. Human ortholog(s) of this gene implicated in colorectal cancer. Is expressed in several structures, including blastomere; digestive system; germ ring; swim bladder; and trunk. Orthologous to human MCC (MCC regulator of WNT signaling pathway).
Genome Resources
Note
The Ensembl Zv9 mcc entry ENSDARG00000087450 lacks an ATG containing exon. 5'-RACE was performed. [Young et al (2014)] ENSDARG00000090139 contains sequence encoding the the N-terminal of the Mcc protein, which is missing in the ENSDARG00000087450 protein coding sequence.
Comparative Information
Expression
All Expression Data
3 figures from Young et al., 2014
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Young et al., 2014
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mcc Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
colorectal cancer Alliance Colorectal cancer, somatic 114500
Associated With mcc Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
Transcripts
Genome Browsers
No data available
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations