Gene

ogdhl

ID

ZDB-GENE-111201-4

Name

oxoglutarate dehydrogenase L

Symbol

ogdhl Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 13 Mapping Details/Browsers

Description

Predicted to have oxoglutarate dehydrogenase (succinyl-transferring) activity and thiamine pyrophosphate binding activity. Predicted to be involved in tricarboxylic acid cycle. Orthologous to human OGDHL (oxoglutarate dehydrogenase like).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ogdhl Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
Yoon-Bellen neurodevelopmental syndrome	Alliance	Yoon-Bellen neurodevelopmental syndrome	619701

Associated With ogdhl Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001017	Dehydrogenase, E1 component
Domain	IPR005475	Transketolase-like, pyrimidine-binding domain
Domain	IPR031717	Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal
Domain	IPR032106	2-oxoglutarate dehydrogenase E1 component, N-terminal domain
Family	IPR011603	2-oxoglutarate dehydrogenase E1 component
Homologous_superfamily	IPR029061	Thiamin diphosphate-binding fold
Homologous_superfamily	IPR042179	Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain superfamily

Domain Details Per Protein

Protein	Length	2-oxoglutarate dehydrogenase E1 component	2-oxoglutarate dehydrogenase E1 component, N-terminal domain	Dehydrogenase, E1 component	Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal	Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain superfamily	Thiamin diphosphate-binding fold	Transketolase-like, pyrimidine-binding domain
UniProtKB:E7FGK9 InterPro

Transcripts

Genome Browsers

NCBI

No data available

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance

Citations