Gene

atr

ID
ZDB-GENE-070912-458
Name
ATR serine/threonine kinase
Symbol
atr Nomenclature History
Previous Names
  • si:dkey-231j24.1
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to have protein serine/threonine kinase activity. Involved in several processes, including determination of left/right symmetry; intrinsic apoptotic signaling pathway in response to DNA damage; and regulation of heart looping. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in Seckel syndrome 1 and pancreatic cancer. Is expressed in hindbrain neural rod; midbrain neural rod; optic vesicle; somite; and tail bud. Orthologous to human ATR (ATR serine/threonine kinase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from Stiff et al., 2016
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With atr Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Seckel syndrome 1 Alliance Seckel syndrome 1 210600
?Cutaneous telangiectasia and cancer syndrome, familial 614564
Associated With atr Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-atr polyclonal Rabbit
  • WB
Abcam plc
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations