Gene

plekhh1

ID

ZDB-GENE-061219-1

Name

pleckstrin homology domain containing, family H (with MyTH4 domain) member 1

Symbol

plekhh1 Nomenclature History

Previous Names

im:6897489
im:7143671
max-1 (1)

Type

protein_coding_gene

Location

Chr: 17 Mapping Details/Browsers

Description

Involved in branching involved in blood vessel morphogenesis. Predicted to localize to cytoskeleton. Is expressed in several structures, including digestive system; hindbrain neural plate; nervous system; pectoral fin bud; and trunk. Orthologous to human PLEKHH1 (pleckstrin homology, MyTH4 and FERM domain containing H1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

9 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

IMAGE:7143671 (12 images)
IMAGE:6897489 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With plekhh1 Human Ortholog

No data available

Associated With plekhh1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000299	FERM domain
Domain	IPR000857	MyTH4 domain
Domain	IPR001849	Pleckstrin homology domain
Domain	IPR019748	FERM central domain
Domain	IPR019749	Band 4.1 domain
Homologous_superfamily	IPR011993	PH-like domain superfamily
Homologous_superfamily	IPR014352	FERM/acyl-CoA-binding protein superfamily
Homologous_superfamily	IPR029071	Ubiquitin-like domain superfamily
Homologous_superfamily	IPR035963	FERM superfamily, second domain
Homologous_superfamily	IPR038185	MyTH4 domain superfamily