Gene

ndufaf1

ID

ZDB-GENE-050306-9

Name

NADH:ubiquinone oxidoreductase complex assembly factor 1

Symbol

ndufaf1 Nomenclature History

Previous Names

fk33c03
wu:fk33c03
zgc:113197 (1)

Type

protein_coding_gene

Location

Chr: 13 Mapping Details/Browsers

Description

Predicted to have unfolded protein binding activity. Predicted to be involved in mitochondrial electron transport, NADH to ubiquinone and mitochondrial respiratory chain complex I assembly. Predicted to localize to mitochondrion. Human ortholog(s) of this gene implicated in mitochondrial complex I deficiency. Orthologous to human NDUFAF1 (NADH:ubiquinone oxidoreductase complex assembly factor 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ndufaf1 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
nuclear type mitochondrial complex I deficiency 11	Alliance	Mitochondrial complex I deficiency, nuclear type 11	618234

Associated With ndufaf1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR013857	NADH:ubiquinone oxidoreductase intermediate-associated protein 30
Family	IPR039131	Complex I intermediate-associated protein 30, mitochondrial
Homologous_superfamily	IPR008979	Galactose-binding-like domain superfamily

Domain Details Per Protein

Protein	Length	Complex I intermediate-associated protein 30, mitochondrial	Galactose-binding-like domain superfamily	NADH:ubiquinone oxidoreductase intermediate-associated protein 30
UniProtKB:Q5CZW0 InterPro	304

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	ndufaf1-202 (1) Ensembl	Havana	846 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	ndufaf1-203 (1) Ensembl	Havana	874 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	ndufaf1-204 (1) Ensembl	Havana	1195 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	ndufaf1-205 (1) Ensembl	Havana	730 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	ndufaf1-206 (1) Ensembl	Havana	1401 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	ndufaf1-208 (1) Ensembl	Havana	444 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	ndufaf1-007 (1) Ensembl	Havana	753 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations