Gene

rbbp8

ID
ZDB-GENE-050220-14
Name
retinoblastoma binding protein 8
Symbol
rbbp8 Nomenclature History
Previous Names
  • zgc:113143
Type
protein_coding_gene
Location
Chr: 24 Mapping Details/Browsers
Description
Predicted to have DNA binding activity and single-stranded DNA endodeoxyribonuclease activity. Predicted to be involved in DNA double-strand break processing involved in repair via single-strand annealing and double-strand break repair via homologous recombination. Predicted to localize to site of double-strand break. Human ortholog(s) of this gene implicated in Seckel syndrome 2. Orthologous to human RBBP8 (RB binding protein 8, endonuclease).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With rbbp8 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Seckel syndrome 2 Alliance Seckel syndrome 2 606744
Jawad syndrome 251255
Pancreatic carcinoma, somatic
Associated With rbbp8 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR013882 DNA endonuclease activator Ctp1, C-terminal
Domain IPR019518 DNA endonuclease Ctp1, N-terminal
Family IPR033316 DNA endonuclease RBBP8-like
Domain Details Per Protein
Protein Length DNA endonuclease activator Ctp1, C-terminal DNA endonuclease Ctp1, N-terminal DNA endonuclease RBBP8-like
UniProtKB:F1R983 651
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations