Gene

sardh

ID

ZDB-GENE-040426-996

Name

sarcosine dehydrogenase

Symbol

sardh Nomenclature History

Previous Names

zgc:56363 (1)

Type

protein_coding_gene

Location

Chr: 10 Mapping Details/Browsers

Description

Predicted to have sarcosine dehydrogenase activity. Predicted to be involved in sarcosine catabolic process. Predicted to localize to mitochondrial matrix. Is expressed in alar plate midbrain region; digestive system; myotome; nervous system; and yolk syncytial layer. Orthologous to human SARDH (sarcosine dehydrogenase).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

7 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

MGC:56363 (11 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With sardh Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
sarcosinemia	Alliance	[Sarcosinemia]	268900

Associated With sardh Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR006076	FAD dependent oxidoreductase
Domain	IPR006222	Aminomethyltransferase, folate-binding domain
Domain	IPR013977	Glycine cleavage T-protein, C-terminal barrel domain
Domain	IPR032503	FAD dependent oxidoreductase, central domain
Family	IPR028896	Aminomethyltransferase-like
Homologous_superfamily	IPR027266	GTP-binding protein TrmE/Aminomethyltransferase GcvT, domain 1
Homologous_superfamily	IPR029043	Glycine cleavage T-protein/YgfZ, C-terminal
Homologous_superfamily	IPR036188	FAD/NAD(P)-binding domain superfamily