Gene

dhx16

ID

ZDB-GENE-030131-8589

Name

DEAH (Asp-Glu-Ala-His) box polypeptide 16

Symbol

dhx16 Nomenclature History

Previous Names

fa91b12
mis (1)
mission impossible (1)
wu:fa91b12
zgc:55590

Type

protein_coding_gene

Location

Chr: 15 Mapping Details/Browsers

Description

Predicted to have RNA binding activity. Involved in endodermal cell differentiation. Predicted to localize to spliceosomal complex. Orthologous to human DHX16 (DEAH-box helicase 16).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

MGC:55590 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 7 figures from 3 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With dhx16 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Neuromuscular disease and ocular or auditory anomalies with or without seizures	618733

Associated With dhx16 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR002464	DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site
Domain	IPR001650	Helicase, C-terminal domain-like
Domain	IPR007502	Helicase-associated domain
Domain	IPR011545	DEAD/DEAH box helicase domain
Domain	IPR011709	DEAD-box helicase, OB fold
Domain	IPR014001	Helicase superfamily 1/2, ATP-binding domain
Domain	IPR048333	Helicase associated domain (HA2), winged-helix domain
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase