Gene
heatr1
- ID
- ZDB-GENE-030131-6378
- Name
- HEAT repeat containing 1
- Symbol
- heatr1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to have snoRNA binding activity. Involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); negative regulation of apoptotic process; and regulation of RNA stability. Predicted to localize to 90S preribosome; small-subunit processome; and t-UTP complex. Human ortholog(s) of this gene implicated in pancreatic ductal carcinoma. Is expressed in eye; forebrain; immature eye; midbrain; and midbrain hindbrain boundary. Orthologous to human HEATR1 (HEAT repeat containing 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Azuma et al., 2006
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR012954 | BP28, C-terminal domain |
| Domain | IPR022125 | U3 small nucleolar RNA-associated protein 10, N-terminal |
| Family | IPR040191 | U3 small nucleolar RNA-associated protein 10 |
| Homologous_superfamily | IPR011989 | Armadillo-like helical |
| Homologous_superfamily | IPR016024 | Armadillo-type fold |
Domain Details Per Protein
| Protein | Length | Armadillo-like helical | Armadillo-type fold | BP28, C-terminal domain | U3 small nucleolar RNA-associated protein 10 | U3 small nucleolar RNA-associated protein 10, N-terminal |
|---|---|---|---|---|---|---|
|
UniProtKB:Q7SY48
|
2159 | |||||
|
UniProtKB:A0A8M3B4F6
|
2160 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| mRNA |
heatr1-201
(1)
|
Havana | 6867 nt |
Interactions and Pathways
No data available
Plasmids
No data available