PUBLICATION
A circadian clock regulates the process of ERG b- and d-wave dominance transition in dark-adapted zebrafish
- Authors
- Ren, J.Q., and Li, L.
- ID
- ZDB-PUB-040609-4
- Date
- 2004
- Source
- Vision Research 44(18): 2147-2152 (Journal)
- Registered Authors
- Li, Lei, Ren, Jason (Qianshen)
- Keywords
- none
- MeSH Terms
-
- Animals
- Circadian Rhythm/physiology*
- Dark Adaptation/physiology*
- Electroretinography*
- Retinal Cone Photoreceptor Cells/physiology
- Retinal Rod Photoreceptor Cells/physiology
- Zebrafish/physiology*
- PubMed
- 15183681 Full text @ Vision Res.
Citation
Ren, J.Q., and Li, L. (2004) A circadian clock regulates the process of ERG b- and d-wave dominance transition in dark-adapted zebrafish. Vision Research. 44(18):2147-2152.
Abstract
In zebrafish, during dark adaptation following bright light adaptation, the dominance of electroretinogram (ERG) b- and d-waves switches. In the early dark adaptation, when visual sensitivity is cone-dominant, both the b- and d-waves are readily recorded. In the late dark adaptation, along with the increase of rod sensitivity, the b-wave becomes dominant whereas the d-wave is gradually lost. The time for the ERG b- and d-wave dominance transition varies between the day and night. The transition requires a longer amount of time in the night and early morning than in the afternoon. This pattern of timing for ERG b- and d-wave dominance transition persists in constant light and can be reversed after exposure to a reversed light-dark cycle. The data suggest that the transition of the dominance of ERG b- and d-waves is regulated by an endogenous circadian clock.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping