Gene

smarcc2

ID

ZDB-GENE-100728-1

Name

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2

Symbol

smarcc2 Nomenclature History

Previous Names

baf170 (1)

Type

protein_coding_gene

Location

Chr: 6 Mapping Details/Browsers

Description

Predicted to have histone binding activity. Predicted to be involved in ATP-dependent chromatin remodeling and positive regulation of transcription, DNA-templated. Predicted to localize to SWI/SNF complex; nBAF complex; and npBAF complex. Orthologous to human SMARCC2 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With smarcc2 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
Coffin-Siris syndrome 8	Alliance	Coffin-Siris syndrome 8	618362

Associated With smarcc2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001005	SANT/Myb domain
Domain	IPR007526	SWIRM domain
Domain	IPR017884	SANT domain
Domain	IPR032448	SMARCC, SWIRM-associated domain
Domain	IPR032450	SMARCC, N-terminal
Domain	IPR032451	SMARCC, C-terminal
Homologous_superfamily	IPR009057	Homeobox-like domain superfamily
Homologous_superfamily	IPR036388	Winged helix-like DNA-binding domain superfamily
Homologous_superfamily	IPR036420	BRCT domain superfamily

Domain Details Per Protein

Protein	Length	BRCT domain superfamily	Homeobox-like domain superfamily	SANT domain	SANT/Myb domain	SMARCC, C-terminal	SMARCC, N-terminal	SMARCC, SWIRM-associated domain	SWIRM domain	Winged helix-like DNA-binding domain superfamily
UniProtKB:A0A8M9Q5E9 InterPro	1036

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	smarcc2-201 (1) Ensembl	Havana	5184 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance

Citations