Gene
gbf1
- ID
- ZDB-GENE-081107-54
- Name
- golgi brefeldin A resistant guanine nucleotide exchange factor 1
- Symbol
- gbf1 Nomenclature History
- Previous Names
-
- sb:eu951
- si:dkey-183c23.1
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to have ARF guanyl-nucleotide exchange factor activity. Predicted to be involved in regulation of ARF protein signal transduction. Is expressed in head. Orthologous to human GBF1 (golgi brefeldin A resistant guanine nucleotide exchange factor 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu951 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 5 figures from Chen et al., 2017
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Charcot-Marie-Tooth disease dominant intermediate A | Alliance | Charcot-Marie-Tooth disease, axonal, type 2GG | 606483 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Armadillo-type fold | Mon2/Sec7/BIG1-like, HUS domain | Sec7, C-terminal domain superfamily | Sec7 domain | Sec7 domain superfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M3BEH1
|
1846 | |||||
|
UniProtKB:A0A286Y9X1
|
1862 | |||||
|
UniProtKB:A0A8M3AYV9
|
1850 | |||||
|
UniProtKB:A0A8M3B513
|
1858 |
Interactions and Pathways
No data available
Plasmids
No data available