Gene

snrnp200

ID

ZDB-GENE-081105-64

Name

small nuclear ribonucleoprotein 200 (U5)

Symbol

snrnp200 Nomenclature History

Previous Names

fb63a09
si:ch211-251j10.5
wu:fb63a09

Type

protein_coding_gene

Location

Chr: 8 Mapping Details/Browsers

Description

Predicted to have RNA binding activity and RNA helicase activity. Predicted to be involved in spliceosome conformational change to release U4 (or U4atac) and U1 (or U11). Predicted to localize to spliceosomal complex. Human ortholog(s) of this gene implicated in retinitis pigmentosa and retinitis pigmentosa 33. Orthologous to human SNRNP200 (small nuclear ribonucleoprotein U5 subunit 200).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

4 figures from 3 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 3 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With snrnp200 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
retinitis pigmentosa 33	Alliance	Retinitis pigmentosa 33	610359

Associated With snrnp200 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001650	Helicase, C-terminal domain-like
Domain	IPR003593	AAA+ ATPase domain
Domain	IPR004179	Sec63 domain
Domain	IPR011545	DEAD/DEAH box helicase domain
Domain	IPR014001	Helicase superfamily 1/2, ATP-binding domain
Domain	IPR041094	Brr2, N-terminal helicase PWI domain
Domain	IPR048863	Pre-mRNA-splicing helicase BRR2-like, plug domain
Homologous_superfamily	IPR014756	Immunoglobulin E-set
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily	IPR035892	C2 domain superfamily
Homologous_superfamily	IPR036388	Winged helix-like DNA-binding domain superfamily
Homologous_superfamily	IPR036390	Winged helix DNA-binding domain superfamily

Domain Details Per Protein

Protein	Length	AAA+ ATPase domain	Brr2, N-terminal helicase PWI domain	C2 domain superfamily	DEAD/DEAH box helicase domain	Helicase, C-terminal domain-like	Helicase superfamily 1/2, ATP-binding domain	Immunoglobulin E-set	P-loop containing nucleoside triphosphate hydrolase	Pre-mRNA-splicing helicase BRR2-like, plug domain	Sec63 domain	Winged helix DNA-binding domain superfamily	Winged helix-like DNA-binding domain superfamily
UniProtKB:B0S754 InterPro	2134

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	snrnp200-201 (1) Ensembl	Havana	7669 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	snrnp200-002 (1) Ensembl	Havana	768 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations