Gene

fosl2

ID
ZDB-GENE-070209-164
Name
FOS like 2, AP-1 transcription factor subunit
Symbol
fosl2 Nomenclature History
Previous Names
  • wu:fl03b09
  • wu:fl17h04
  • xx:fl17h04
  • zgc:158347
Type
protein_coding_gene
Location
Chr: 17 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in regulation of cardiac muscle cell myoblast differentiation. Predicted to localize to nucleus. Is expressed in head; presumptive bulbus arteriosus; presumptive cardiac ventricle heart tube; and trunk. Orthologous to human FOSL2 (FOS like 2, AP-1 transcription factor subunit).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
8 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from Jahangiri et al., 2016
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With fosl2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Aplasia cutis-enamel dysplasia syndrome 620789
Associated With fosl2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR004827 Basic-leucine zipper domain
Family IPR000837 AP-1 transcription factor
Homologous_superfamily IPR046347 Basic-leucine zipper domain superfamily
Domain Details Per Protein
Protein Length AP-1 transcription factor Basic-leucine zipper domain Basic-leucine zipper domain superfamily
UniProtKB:A2RUX8 341
UniProtKB:A0A8M2BKU3 302
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations