Gene
cav3
- ID
- ZDB-GENE-050522-426
- Name
- caveolin 3
- Symbol
- cav3 Nomenclature History
- Previous Names
-
- im:6902906
- zgc:109710
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to have molecular adaptor activity. Involved in muscle cell fate commitment; notochord cell development; and striated muscle cell differentiation. Localizes to sarcolemma. Predicted to colocalize with caveola and focal adhesion. Used to study muscular dystrophy. Human ortholog(s) of this gene implicated in intrinsic cardiomyopathy (multiple); isolated elevated serum creatine phosphokinase levels; and muscle tissue disease (multiple). Is expressed in several structures, including adaxial cell; heart; musculature system; notochord; and pectoral fin. Orthologous to human CAV3 (caveolin 3).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 12 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6902906 (11 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Hippe et al., 2011
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Human Disease | Fish | Conditions | Citations |
---|---|---|---|
muscular dystrophy | WT + MO2-cav3 | standard conditions | Nixon et al., 2005 |
muscular dystrophy | WT + MO1-cav3 | standard conditions | Nixon et al., 2005 |
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | Caveolin | Caveolin, conserved site |
---|---|---|---|
UniProtKB:Q6YLH7
|
150 |
Interactions and Pathways
No data available
Plasmids