Gene

nop2

ID

ZDB-GENE-050309-7

Name

NOP2 nucleolar protein homolog (yeast)

Symbol

nop2 Nomenclature History

Previous Names

cb164 (1)
im:6893299 (1)
sb:cb164
si:dkey-91i17.1

Type

protein_coding_gene

Location

Chr: 16 Mapping Details/Browsers

Description

Predicted to have rRNA (cytosine-C5-)-methyltransferase activity. Predicted to be involved in maturation of LSU-rRNA and rRNA base methylation. Predicted to localize to nucleolus. Is expressed in several structures, including digestive system; mesoderm; nervous system; neural tube; and pectoral fin. Orthologous to human NOP2 (NOP2 nucleolar protein).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

12 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

cb164 (9 images)
IMAGE:6893299 (10 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With nop2 Human Ortholog

No data available

Associated With nop2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018314	Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site
Domain	IPR001678	SAM-dependent methyltransferase RsmB-F/NOP2-type domain
Domain	IPR011023	Nop2p
Domain	IPR031341	Ribosomal RNA small subunit methyltransferase F, N-terminal
Family	IPR023267	RNA (C5-cytosine) methyltransferase
Family	IPR023273	RNA (C5-cytosine) methyltransferase, NOP2
Homologous_superfamily	IPR029063	S-adenosyl-L-methionine-dependent methyltransferase superfamily

Domain Details Per Protein

Protein	Length	Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site	Nop2p	Ribosomal RNA small subunit methyltransferase F, N-terminal	RNA (C5-cytosine) methyltransferase	RNA (C5-cytosine) methyltransferase, NOP2	S-adenosyl-L-methionine-dependent methyltransferase superfamily	SAM-dependent methyltransferase RsmB-F/NOP2-type domain
UniProtKB:A0A8M1P6F7 InterPro	739

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	nop2-201 (1) Ensembl	Havana	2767 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	nop2-002 (1) Ensembl	Havana	797 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations