Gene

dph5

ID
ZDB-GENE-041114-85
Name
diphthamide biosynthesis 5
Symbol
dph5 Nomenclature History
Previous Names
  • zgc:101823
Type
protein_coding_gene
Location
Chr: 22 Mapping Details/Browsers
Description
Predicted to have diphthine synthase activity. Predicted to be involved in peptidyl-diphthamide biosynthetic process from peptidyl-histidine. Orthologous to human DPH5 (diphthamide biosynthesis 5).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With dph5 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
neurodevelopmental disorder with short stature, prominent forehead, and feeding difficulties Alliance Neurodevelopmental disorder with short stature, prominent forehead, and feeding difficulties 620070
Associated With dph5 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000878 Tetrapyrrole methylase
Family IPR004551 Diphthine synthase
Homologous_superfamily IPR014776 Tetrapyrrole methylase, subdomain 2
Homologous_superfamily IPR014777 Tetrapyrrole methylase, subdomain 1
Homologous_superfamily IPR035996 Tetrapyrrole methylase superfamily
Domain Details Per Protein
Protein Length Diphthine synthase Tetrapyrrole methylase Tetrapyrrole methylase, subdomain 1 Tetrapyrrole methylase, subdomain 2 Tetrapyrrole methylase superfamily
UniProtKB:A0A0R4IU56 288
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations