Gene
tab2
- ID
- ZDB-GENE-040426-933
- Name
- TGF-beta activated kinase 1 (MAP3K7) binding protein 2
- Symbol
- tab2 Nomenclature History
- Previous Names
-
- Tab2 (1)
- map3k7ip2
- zgc:77446
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to have K63-linked polyubiquitin modification-dependent protein binding activity. Involved in chordate embryonic development; convergent extension involved in gastrulation; and heart development. Is expressed in bulbus arteriosus; dorsal aorta; and posterior cardinal vein. Orthologous to human TAB2 (TGF-beta activated kinase 1 (MAP3K7) binding protein 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thienpont et al., 2010
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Thienpont et al., 2010
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Congenital heart defects, nonsyndromic, 2 | 614980 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | TAB2/3, CUE domain | Ubiquitin system component CUE | Zinc finger, RanBP2-type | Zinc finger, RanBP2-type superfamily |
|---|---|---|---|---|---|
|
UniProtKB:A0A8M6Z392
|
750 | ||||
|
UniProtKB:Q5RFW2
|
711 |
Interactions and Pathways
No data available
Plasmids
No data available