Gene

dock2

ID
ZDB-GENE-031125-1
Name
dedicator of cytokinesis 2
Symbol
dock2 Nomenclature History
Previous Names
  • cb1005 (1)
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Is expressed in macrophage. Orthologous to human DOCK2 (dedicator of cytokinesis 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from Thisse et al., 2001
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With dock2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
immunodeficiency 40 Alliance Immunodeficiency 40 616433
Associated With dock2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR027357 DOCKER domain
Domain IPR046769 DOCKER, Lobe A
Domain IPR046770 DOCKER, Lobe B
Domain IPR046773 DOCKER, Lobe C
Family IPR026791 Dedicator of cytokinesis
Homologous_superfamily IPR043161 Dedicator of cytokinesis, C-terminal, lobe A
Homologous_superfamily IPR043162 Dedicator of cytokinesis, C-terminal, lobe C
Domain Details Per Protein
Protein Length Dedicator of cytokinesis Dedicator of cytokinesis, C-terminal, lobe A Dedicator of cytokinesis, C-terminal, lobe C DOCKER domain DOCKER, Lobe A DOCKER, Lobe B DOCKER, Lobe C
UniProtKB:A0A8M1RM83 678
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations