Gene

shc1

ID
ZDB-GENE-030131-2538
Name
SHC (Src homology 2 domain containing) transforming protein 1
Symbol
shc1 Nomenclature History
Previous Names
  • si:dkey-246i14.4
  • wu:fc10h03 (1)
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to have receptor tyrosine kinase binding activity. Involved in angiogenesis. Predicted to localize to plasma membrane. Orthologous to human SHC1 (SHC adaptor protein 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Sweet et al., 2012
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With shc1 Human Ortholog
No data available
Associated With shc1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000980 SH2 domain
Domain IPR006019 Phosphotyrosine interaction domain, Shc-like
Domain IPR006020 PTB/PI domain
Domain IPR035676 SH2 adaptor protein C, SH2 domain
Homologous_superfamily IPR011993 PH-like domain superfamily
Homologous_superfamily IPR036860 SH2 domain superfamily
Domain Details Per Protein
Protein Length PH-like domain superfamily Phosphotyrosine interaction domain, Shc-like PTB/PI domain SH2 adaptor protein C, SH2 domain SH2 domain SH2 domain superfamily
UniProtKB:A0A8M6Z1Z9 593
UniProtKB:E9QCZ8 449
UniProtKB:E7F3T0 454
UniProtKB:A0A8M3AJ37 575
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations