Gene
dnah9
- ID
- ZDB-GENE-020925-1
- Name
- dynein, axonemal, heavy chain 9
- Symbol
- dnah9 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to have ATP-dependent microtubule motor activity, minus-end-directed; dynein intermediate chain binding activity; and dynein light intermediate chain binding activity. Involved in epithelial cilium movement involved in determination of left/right asymmetry. Predicted to localize to axoneme; dynein complex; and motile cilium. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia. Is expressed in several structures, including mesoderm; nervous system; neural tube; pleuroperitoneal region; and tail bud. Orthologous to human DNAH9 (dynein axonemal heavy chain 9).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 33 figures from 18 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:63607 (11 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Chen et al., 2022
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| primary ciliary dyskinesia 40 | Alliance | Ciliary dyskinesia, primary, 40 | 618300 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR013594 | Dynein heavy chain, tail |
Domain Details Per Protein
| Protein | Length | Dynein heavy chain, tail |
|---|---|---|
|
UniProtKB:Q7SY17
|
614 |
Interactions and Pathways
No data available
Plasmids
No data available