Gene

dlg1a

ID
ZDB-GENE-010724-8
Name
discs large MAGUK scaffold protein 1a
Symbol
dlg1a Nomenclature History
Previous Names
  • dlg1
  • SAP-97A (1)
  • wu:fc34d02
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to have phosphatase binding activity and protein kinase binding activity. Predicted to be involved in several processes, including actin cytoskeleton organization; endothelial cell proliferation; and establishment or maintenance of epithelial cell apical/basal polarity. Predicted to colocalize with ionotropic glutamate receptor complex. Human ortholog(s) of this gene implicated in invasive ductal carcinoma. Is expressed in nervous system; neural crest; neural tube; pigment cell; and trigeminal placode. Orthologous to human DLG1 (discs large MAGUK scaffold protein 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
11 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With dlg1a Human Ortholog
No data available
Associated With dlg1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR020590 Guanylate kinase, conserved site
Domain IPR001478 PDZ domain
Domain IPR004172 L27 domain
Domain IPR008144 Guanylate kinase-like domain
Domain IPR008145 Guanylate kinase/L-type calcium channel beta subunit
Domain IPR015143 L27-1
Domain IPR019583 Disks large homolog 1-4, PDZ-associated domain
Domain IPR019590 Disks large homologue 1, N-terminal PEST domain
Family IPR016313 Disks large 1-like
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily IPR036034 PDZ superfamily
Homologous_superfamily IPR036892 L27 domain superfamily
Domain Details Per Protein
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations